Location: Blowing Rock Hwy and Valley Blvd, Blowing Rock Reassurance shield as the business loop begins, omitting US-221. Location: Blowing Rock Hwy and Main St, Blowing Rock A few blocks later, turn right to stay on 221 south. Location: Blowing Rock Hwy and Main St, Blowing Rock Turn right for 221 south. Stay straight to … Continue reading U.S. Route 221, US-321/US-321 Bus to US-321 Bus